♥ Book Title : Principles of Clinical Pharmacology
☯ Full Synopsis : "Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. * Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions. * Offers an expanded regulatory section that addresses US and international issues and guidelines. * Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response. * Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III."Article| Arthur J. Atkinson| Statement ..."
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♥ Book Title : Principles of Clinical Pharmacology
☯ Full Synopsis : "This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. * Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy. * Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course. * Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study. * Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry. * Expanded coverage of pharmacogenetics * Expanded coverage of drug transporters and their role in interactions * Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions * A new chapter on drug discovery that focuses on oncologic agents * Inclusion of therapeutic antibodies in chapter on biotechnology products"Article| Arthur J. Atkinson, Jr.| Statement ..."
♥ Book Title : Small Animal Clinical Pharmacology
☯ Full Synopsis : "Small Animal Clinical Pharmacology is a practical, clinically-oriented pharmacology text designed to provide the veterinary student and practitioner with all the relevant information needed when designing drug treatment regimens for pets in small animal veterinary practice. Comprehensively updated and revised, the second edition of this core text covers essential new information on drugs used in the management of a range of presenting conditions including heart disease and cardiac arrhythmias. For the second edition new authors, superb new illustrations and a second colour have all been introduced. With its unique approach combining a thorough understanding of the pharmacological action of drugs with a basic understanding of the relevant physiology and pathophysiology of systems and tissues affected, Small Animal Clinical Pharmacology continues to be an indispensable book for all veterinary students and practitioners. Organised by drug class in a uniform and detailed structure which means it is easy to locate key information on dose rates, routes of administration, drug interactions and special considerations at a glance Key chapters based around treatment of disorders of particular body systems, eg cardiovascular and thyroid disorders Essential introductory chapters covering pharmacokinetics, general pharmacological principles and adverse reactions for a thorough basic grounding in the subject All authors are experienced clinicians and recognised experts in their field who bring a down to earth and practical approach to the text"Article| Jill E. Maddison| Statement ..."
♥ Book Title : Clinical Pharmacology and Therapeutics
☯ Full Synopsis : "Clinical Pharmacology and Therapeutics Lecture Notesprovides a clear and accessible overview of all the key prescribingtopics needed for medical finals and beyond. Detailed coverage anddiscussion of pharmacology in a clinical context, combined with aneasy-to-understand, readable style, helps improve and testunderstanding of pharmacological principles and reasoning onrotation and into the foundation years. Key features for this edition include: • Clinical scenarios to root each chapter firmly in areal-life setting • Prescribing points flagging up important issues ofclinical relevance • Expanded sections on drugs you may need in a hurry,prescribing and its pitfalls, and paediatric prescribing • A self-assessment section to test your knowledge andhelp prepare for examinations Clinical Pharmacology and Therapeutics Lecture Notes isan ideal resource for all medical students, junior doctors, andother prescribers, whether learning how pharmacological principlesrelate to clinical situations, brushing up on the basics while onrotation, or looking for a comprehensive overview of prescribingand therapeutics."Article| Gerard A. McKay| Statement ..."
♥ Book Title : Oxford Textbook of Clinical Pharmacology and Drug Therapy
☯ Full Synopsis : "Completely updated, the new edition of the Oxford Textbook of Clinical Pharmacology and Drug Therapy continues to provide medical students and clinicians with a unique insight into why drugs have their therapeutic effects, by presenting the basic principles of pharmacology as they affect the patient. An understanding of these principles is essential for rational, safe, effective, and economical prescribing. The text shows how knowledge of the scientific basis of drug action is applied in a clinical context to devise the most effective treatments for disease and to maximize the therapeutic effects of the drugs being used. This new edition includes an appraisal of the value of evidence-based medicine and a greater discussion of issues in genetics. There are specialist contributors for areas of infectious disease, gastrointestinal disorders, blood disorders, general anaesthesia, cancer chemotherapy, and immunosuppression. The revision also includes updates to both the pharmacopoeia and the drug therapy section, to reflect new developments in both available drugs and in their use."Article| David Grahame Grahame-Smith| Statement ..."
♥ Book Title : Concise Clinical Pharmacology
☯ Full Synopsis : "Concise Clinical Pharmacology is a thorough introduction to the subject from which students can gain a rapid understanding of individual topics within the discipline. Pharmacological principles and mechanisms are covered, with a focus on the therapeutic use of the drugs. Concise Clinical Pharmacology will be invaluable to undergraduate pharmacy students, and clinical medical students. the strong clinical focus should also appeal to practitioners."Article| Ben Greenstein| Statement ..."
♥ Book Title : Anesthetic Pharmacology
☯ Full Synopsis : "In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period."Article| Alex S. Evers| Statement ..."
♥ Book Title : Pharmacology in Clinical Practice
☯ Full Synopsis : "Pharmacology in Clinical Practice describes basic pharmacology, clinical pharmacology, including the pharmacology of important drug groups. The author reviews the general principles of clinical pharmacology including drug actions, absorption, disposition, and excretion. Most drugs are xenobiotics—compounds foreign and harmful to human living tissues. Drugs should be properly metabolized and converted to nontoxic substance before being excreted either through spontaneous changes not mediated by enzymes or through transformation by enzyme systems. The author also discusses pharmacokinetics, including drug plasma concentration, absorption, first-pass metabolism, distribution and elimination. The author addresses pharmacogenetics that deal with possible different responses to drug intake due to factors such as age, sex, liver or renal disease, smoking, diet. The book tackles other drugs, their uses, and characteristics such as antibacterial agents, obesity drug, cytotoxic drugs or those used in chemotherapy medicine. The author explains the diagnosis of drug ingestion, clinical signs of overdose, clinical course, and prophylactic measures for users to avoid drug overdose or self-poisoning. This book is intended for medical undergraduates, pharmaceutical technicians, pharmacists, students or professors in pharmacology or general medicine."Article| Richard Lancaster| Statement ..."
♥ Book Title : Equine Clinical Pharmacology
☯ Full Synopsis : ""This text is fully referenced and current prescribing practice for horses is backed up by scientific research published in the literature: for example, direct evidence from equine studies versus extrapolation from studies in other species is reviewed by the contributors. A formulary of generic drug names that includes dosages and routes of administration, with special emphasis on products and dose rates approved for use in horses, is included at the end of the book."--BOOK JACKET."Article| Joseph Bertone| Statement ..."
♥ Book Title : Neurological Clinical Pharmacology
☯ Full Synopsis : "In recent years there has been much interest in clinical pharmacology and its ap plication to the treatment of disease, including disease of the nervous system. At the same time there have been major advances in basic neuropharmacology. The aim of this book is to integrate clinical pharmacology with basic neuropharmacology and clinical neurology. The book discusses, in the light of clinical pharmacology, and par ticularly pharmacokinetics, the treatment of those disorders of the nervous system that are conventionally managed by the clinical neurologist. Matters pertaining to psychopharmacology have been deliberately excluded except in so far as they impinge on ordinary clinical neurological practice. The extent to which various disorders have been considered has depended partly on their importance to the clinical neurologist practising in non-tropical areas, and partly on the amount of data available relating to the relevant drug treatment. Thus the book is directed at clinical neurologists and those intending to practise clinical neurology. However it also contains material of in terest to the general physician, paediatrician, psychiatrist and clinical pharmacologist. Although the emphasis in this book is on drug treatment, to preserve balance it has seemed desirable to discuss briefly certain non-pharmacological aspects of thera peutics. The orderly methodical approach used in the book offers two possible advan tages: first, once the reader is familiar with the approach (see Guide to the Use of This Book, p."Article| M. Eadie| Statement ..."
♥ Book Title : Avery's Drug Treatment
☯ Full Synopsis : ""Article| Graeme S. Avery| Statement ..."
♥ Book Title : Topics in Clinical Pharmacology and Therapeutics
☯ Full Synopsis : "Dr. Maronde has performed a major service in bringing together a superb array of scholars and clinicians to discuss not only the basic principles in therapeutics and clinical pharmacology but also the application of those principles to a wide range of clinical problems. Inclusion of chapters on adverse drug reactions, drug overdose, nonmedical prescription drug use, physician prescribing patterns, and the pharmaceutical industry makes this a particularly valuable book for clinicians. It is increasingly important that clinicians be well grounded in the principles of pharmacodynamics and pharmacokinetics because more and more of our patients are aging and cannot be treated as young or middle-aged adults. Elderly patients are liable to either drug overdose or underdose if traditional dosage formulas are followed because of changes in drug metabolism, drug distribution within the body, drug excretion, or changes in receptor site sensitivity. Because the elderly often present with mUltiple chronic diseases and require a variety of medications, they are more prone to medication errors, drug-drug interactions, and adverse drug reactions. The inclusion of three excellent chapters relating to drug-drug interactions, adverse drug reactions, and drug overdose is most welcome and is a valuable addition to this outstanding text on therapeutics and clinical pharmacology. Adverse drug reactions present a potentially serious problem for any patient for whom drugs are prescribed and particularly for those who must take multiple prescriptions."Article| Robert F. Maronde| Statement ..."